Detalhe da pesquisa
1.
VSIG4 interaction with heparan sulfates inhibits VSIG4-complement binding.
Glycobiology
; 33(7): 591-604, 2023 08 14.
Artigo
Inglês
| MEDLINE | ID: mdl-37341346
2.
Kappa-on-Heavy (KoH) bodies are a distinct class of fully-human antibody-like therapeutic agents with antigen-binding properties.
Proc Natl Acad Sci U S A
; 117(1): 292-299, 2020 01 07.
Artigo
Inglês
| MEDLINE | ID: mdl-31879340
3.
High affinity human Fc specific monoclonal antibodies for capture kinetic analyses of antibody-antigen interactions.
Anal Biochem
; 640: 114455, 2022 03 01.
Artigo
Inglês
| MEDLINE | ID: mdl-34788604
4.
Humanized C3 Mouse: A Novel Accelerated Model of C3 Glomerulopathy.
J Am Soc Nephrol
; 32(1): 99-114, 2021 01.
Artigo
Inglês
| MEDLINE | ID: mdl-33288630
5.
Dual blockade of IL-4 and IL-13 with dupilumab, an IL-4Rα antibody, is required to broadly inhibit type 2 inflammation.
Allergy
; 75(5): 1188-1204, 2020 05.
Artigo
Inglês
| MEDLINE | ID: mdl-31838750
6.
The impact of different human IgG capture molecules on the kinetics analysis of antibody-antigen interaction.
Anal Biochem
; 593: 113580, 2020 03 15.
Artigo
Inglês
| MEDLINE | ID: mdl-31926892
7.
IL-33 blockade affects mediators of persistence and exacerbation in a model of chronic airway inflammation.
J Allergy Clin Immunol
; 144(6): 1624-1637.e10, 2019 12.
Artigo
Inglês
| MEDLINE | ID: mdl-31562870
8.
Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates.
J Infect Dis
; 218(suppl_5): S612-S626, 2018 11 22.
Artigo
Inglês
| MEDLINE | ID: mdl-29860496
9.
Pre- and postexposure efficacy of fully human antibodies against Spike protein in a novel humanized mouse model of MERS-CoV infection.
Proc Natl Acad Sci U S A
; 112(28): 8738-43, 2015 Jul 14.
Artigo
Inglês
| MEDLINE | ID: mdl-26124093
10.
Mice with megabase humanization of their immunoglobulin genes generate antibodies as efficiently as normal mice.
Proc Natl Acad Sci U S A
; 111(14): 5153-8, 2014 Apr 08.
Artigo
Inglês
| MEDLINE | ID: mdl-24706856
11.
Aflibercept exhibits VEGF binding stoichiometry distinct from bevacizumab and does not support formation of immune-like complexes.
Angiogenesis
; 19(3): 389-406, 2016 07.
Artigo
Inglês
| MEDLINE | ID: mdl-27234973
12.
Breast Cancers Detected at Screening MR Imaging and Mammography in Patients at High Risk: Method of Detection Reflects Tumor Histopathologic Results.
Radiology
; 280(3): 716-22, 2016 09.
Artigo
Inglês
| MEDLINE | ID: mdl-27097237
13.
Blocking common γ chain cytokine signaling ameliorates T cell-mediated pathogenesis in disease models.
Sci Transl Med
; 15(678): eabo0205, 2023 01 11.
Artigo
Inglês
| MEDLINE | ID: mdl-36630481
14.
Preclinical, randomized phase 1, and compassionate use evaluation of REGN4461, a leptin receptor agonist antibody for leptin deficiency.
Sci Transl Med
; 15(723): eadd4897, 2023 11 22.
Artigo
Inglês
| MEDLINE | ID: mdl-37992152
15.
Cytokine traps: multi-component, high-affinity blockers of cytokine action.
Nat Med
; 9(1): 47-52, 2003 Jan.
Artigo
Inglês
| MEDLINE | ID: mdl-12483208
16.
Generation of T-cell-redirecting bispecific antibodies with differentiated profiles of cytokine release and biodistribution by CD3 affinity tuning.
Sci Rep
; 11(1): 14397, 2021 07 13.
Artigo
Inglês
| MEDLINE | ID: mdl-34257348
17.
Enhanced IL-36R signaling promotes barrier impairment and inflammation in skin and intestine.
Sci Immunol
; 5(54)2020 12 18.
Artigo
Inglês
| MEDLINE | ID: mdl-33443029
18.
Inhibition of complement pathway activation with Pozelimab, a fully human antibody to complement component C5.
PLoS One
; 15(5): e0231892, 2020.
Artigo
Inglês
| MEDLINE | ID: mdl-32384086
19.
Studies in humanized mice and convalescent humans yield a SARS-CoV-2 antibody cocktail.
Science
; 369(6506): 1010-1014, 2020 08 21.
Artigo
Inglês
| MEDLINE | ID: mdl-32540901
20.
A class of costimulatory CD28-bispecific antibodies that enhance the antitumor activity of CD3-bispecific antibodies.
Sci Transl Med
; 12(525)2020 01 08.
Artigo
Inglês
| MEDLINE | ID: mdl-31915305